🎉 $25 OFF your evaluation — Use code 25OFF at checkout

Hybrid

Skunk #1

Also known as: Skunk, Original Skunk

Afghan Ă— Mexican Ă— Colombian

Skunk #1 is a hybrid strain (Afghan Ă— Mexican Ă— Colombian) with THC levels of 15-20%. It features a Myrcene-dominant terpene profile and is known for euphoric and happy. Best used during any time of day.

THC

15-20%

CBD

0.1-0.5%

Best Time

Any Time

Primary Effects

EuphoricHappyRelaxedUplifted

Flavor Notes

Skunky, Earthy, Sweet, Pungent

Aroma

Intense skunky aroma with earthy sweetness and pungent notes

Research Sources

8 peer-reviewed studies

Verified Via

PubMed / DOI

Evidence

Research-Backed

Updated

December 2025

Every claim cites peer-reviewed research
How We Research

About Skunk #1

Skunk #1 is one of the most influential strains in cannabis history, created by Sacred Seeds in the late 1970s. Combining Afghan, Mexican, and Colombian genetics, it was the first stabilized hybrid with predictable traits, revolutionizing cannabis breeding. Its genetics are found in hundreds of modern strains.

Terpene Profile

Myrcenedominant
Earthy, musky, clove-like~0.55%

Primary research: Sedation & Relaxation

~0.42%
Limonenesecondary
Citrus, lemon, orange~0.28%

Primary research: THC Anxiety Reduction

Concentration Levels

Dominant (>1.0%)
Primary (0.5-1.0%)
Secondary (0.1-0.5%)
Trace (<0.1%)

Cannabinoid Profile

THCPsychoactive

15-20%

Pain Relief

0.1-0.5%

Seizure Reduction

Therapeutic Profile Matches

Based on Skunk #1's terpene and cannabinoid profile, it may be well-suited for these therapeutic applications:

migraines

60%
Moderate Match
  • High myrcene content supports migraines & headaches
  • thc dominant ratio matches profile
  • Best used anytime, aligning with condition needs

ptsd

52%
Moderate Match
  • High myrcene content supports ptsd & trauma
  • thc dominant ratio matches profile

nausea

51%
Moderate Match
  • High limonene content supports nausea & appetite loss
  • thc dominant ratio matches profile
  • Best used anytime, aligning with condition needs

muscle spasms

51%
Moderate Match
  • High myrcene content supports muscle spasms & spasticity

Match scores are theoretical

These scores are based on terpene/cannabinoid research and do not guarantee specific effects. Individual responses vary significantly. Always consult a healthcare provider.

Frequently Asked Questions

Why is Skunk #1 so important?

Skunk #1 was the first stabilized, predictable cannabis hybrid. Before Skunk, breeding was unpredictable. It revolutionized cannabis cultivation and is in the genetics of hundreds of modern strains.

What strains come from Skunk #1?

Countless strains descend from Skunk #1 including Cheese, Super Skunk, Lemon Skunk, and many others. It's used in the breeding of almost every modern hybrid family.

Quick Facts

Type
Hybrid
Genetics
Afghan Ă— Mexican Ă— Colombian
Breeder
Sacred Seeds
Best Time of Use
Any Time
Availability
common
Grow Difficulty
easy

Want to try Skunk #1? Get your medical marijuana card today.

Get Your Card

Educational Information

This content is for educational purposes only and is not medical advice. Consult a healthcare provider before using cannabis products.

Strain Variability

Profiles vary between batches, growers, and growing conditions. Always check lab test results for the specific product you're purchasing.

Beyond Indica/Sativa

Effects are better predicted by cannabinoid and terpene profiles than strain classification. Focus on the chemistry, not the label.

Understanding Therapeutic Profiles

Learn how terpenes and cannabinoids work together to create each strain's unique effects and therapeutic potential through the entourage effect.

Learn About Therapeutic Profiles