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sesquiterpene

Bisabolol

α-Bisabolol

Pronounced: bih-SAB-oh-lol

Bisabolol is a sesquiterpene terpene with a delicate floral, sweet, chamomile-like aroma. It's also found naturally in Chamomile (German & Roman), Candeia tree. Research suggests bisabolol well-established skin-soothing and wound-healing properties, though more human studies are needed.

Boiling Point

307°F (153°C)

Aroma

Delicate floral

Also Found In

Chamomile (German & Roman)Candeia tree

Aroma Profile:
Delicate floral, sweet, chamomile-like

What is Bisabolol?

α-Bisabolol is best known as the primary active component of chamomile and is highly valued in skincare for its soothing properties. Research shows gastroprotective effects, wound healing acceleration, and neuroprotective potential against amyloid-beta toxicity relevant to Alzheimer's disease.

How Bisabolol Works

Bisabolol shows anti-irritant and anti-inflammatory activity through multiple mechanisms including COX-2 and iNOS inhibition. It also enhances the absorption of other compounds through skin and mucous membranes (penetration enhancer). Research demonstrates significant gastroprotective effects via TRPV1 receptors.

Researched Effects

Skin Soothing & Wound Healing

Strong Evidence

Extensively researched in skincare; enhances wound healing with reduced scar formation.

✓ Compliant Language

Well-established skin-soothing and wound-healing properties

✗ Avoid Saying

Treats skin conditions

Gastroprotective

Moderate Evidence

Significant gastroprotective effects mediated by TRPV1 receptors.

✓ Compliant Language

Research shows gastro-protective properties

✗ Avoid Saying

Treats ulcers

Anti-inflammatory

Moderate Evidence

Demonstrates anti-inflammatory activity through COX-2 and iNOS inhibition.

✓ Compliant Language

Research supports anti-inflammatory properties

✗ Avoid Saying

Reduces inflammation

Understanding Evidence Levels

Strong EvidenceMultiple peer-reviewed clinical trials support this effect
Moderate EvidenceSupported by preclinical studies and limited clinical data
Emerging ResearchEarly research shows promise but more studies needed
Anecdotal ReportsBased on user reports; limited scientific research

Safety Information

Bisabolol is extremely well-tolerated and used extensively in sensitive-skin products and baby care. Excellent safety profile.

Scientific References

A Review on α-Bisabolol: Its Biological Properties

Kim S, et al. • Journal of Oleo Science (2014)

PubMed ID: 24829134

Comprehensive review of bisabolol biological properties including skin-soothing and anti-inflammatory effects.

α-Bisabolol loaded electrospun PLA nanofibrous for wound healing

Eddin LB, et al. • Pharmaceutics (2022)

Demonstrated enhanced wound healing with reduced scar formation.

Gastroprotective effect of α-bisabolol on ethanol-induced gastric ulcer

Cho JY, et al. • Archives of Pharmacal Research (2022)

Significant gastroprotective effects mediated by TRPV1 receptors.

Anti-inflammatory effects of α-bisabolol

Kim S, et al. • Archives of Pharmacal Research (2011)

PubMed ID: 21656347

Investigated anti-inflammatory mechanisms via COX-2 and iNOS inhibition.

Frequently Asked Questions

What is bisabolol?

Bisabolol (α-bisabolol) is a gentle, floral terpene and the primary active component of chamomile. It's valued for its soothing properties in both cannabis and skincare.

Is bisabolol good for skin?

Yes! Bisabolol is extensively used in skincare, especially for sensitive skin, due to its well-documented anti-irritant properties. It's found in many baby care products.

Quick Facts

Full Name
α-Bisabolol
Category
sesquiterpene
Boiling Point
307°F (153°C)
Aroma
Delicate floral, sweet, chamomile-like
Strains High in Bisabolol
Harle-TsuACDCOracleHeadbandPink KushOG Shark

Looking for strains high in Bisabolol? Our doctors can help you find the right product.

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Educational Information

This content is for educational purposes only and is not medical advice. Consult a healthcare provider before using cannabis products.

Strain Variability

Terpene profiles vary significantly between batches, growers, and growing conditions—even for the same strain name. Always check lab test results.

Indica/Sativa Note

The indica/sativa distinction is largely marketing. Effects are better predicted by cannabinoid and terpene profiles than strain classification.