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Myrcene
β-Myrcene
Pronounced: MUR-seen
Myrcene is a monoterpene terpene with a earthy, musky, clove-like aroma. It's also found naturally in Mangoes, Hops, Lemongrass. Research suggests myrcene may promote relaxation and support restful sleep, though more human studies are needed.
Boiling Point
332°F (167°C)
Aroma
Earthy
Also Found In
Aroma Profile:
Earthy, musky, clove-like
What is Myrcene?
Myrcene is the most abundant terpene in most cannabis varieties, often comprising over 50% of the total terpene profile. This monoterpene is responsible for the characteristic "dank" aroma of many cannabis strains. Strains with >0.5% myrcene are often associated with the sedating "couch-lock" effect. Research suggests myrcene may potentiate the anti-nociceptive properties of cannabinoids.
How Myrcene Works
Myrcene is believed to work primarily through the endocannabinoid system and GABA receptors. Research suggests it may enhance cannabinoid absorption across the blood-brain barrier, potentially increasing the effects of THC. It also interacts with adenosine receptors, which are involved in sleep and relaxation. A key citation: "β-Myrcene contained within the cannabis plant may potentiate the innate anti-nociceptive properties of cannabinoids" (Surendran et al., 2021).
Researched Effects
Sedation & Relaxation
Moderate EvidencePreclinical studies show myrcene has muscle-relaxant and sedative properties at high doses.
✓ Compliant Language
May promote relaxation and support restful sleep
✗ Avoid Saying
Cures insomnia or is a sedative
Anti-inflammatory
Moderate EvidenceAnimal studies demonstrate anti-inflammatory activity comparable to some traditional remedies.
✓ Compliant Language
Shows anti-inflammatory properties in preclinical research
✗ Avoid Saying
Reduces inflammation or treats inflammatory conditions
Sources
Analgesic Support
Moderate EvidenceMay potentiate the pain-relieving effects of cannabinoids through synergistic interaction.
✓ Compliant Language
May support the body's response to discomfort
✗ Avoid Saying
Treats or relieves pain
Understanding Evidence Levels
Safety Information
Myrcene is Generally Recognized as Safe (GRAS) by the FDA for use in food. A 2023 study found myrcene did not impair simulated driving performance, though caution is still advised when combining with THC.
Scientific References
Surendran S, et al. • Frontiers in Nutrition (2021)
Comprehensive review: β-myrcene may potentiate the anti-nociceptive properties of cannabinoids.
Sewell RA, et al. • Cannabis and Cannabinoid Research (2023)
Found myrcene alone did not significantly impair simulated driving performance.
do Vale TG, et al. • Phytomedicine (2002)
PubMed ID: 12587690
Demonstrated dose-dependent sedative and motor-relaxant effects in mice.
Lorenzetti BB, et al. • Journal of Ethnopharmacology (1991)
PubMed ID: 1753786
Found peripheral analgesic activity in animal models.
Rao VS, et al. • Journal of Pharmacy and Pharmacology (1990)
PubMed ID: 1983142
Investigated pain-modulating mechanisms in animal studies.
Frequently Asked Questions
What is myrcene?
Myrcene (β-myrcene) is the most abundant terpene in cannabis, often making up over 50% of a strain's terpene profile. It has an earthy, musky aroma and is also found in mangoes, hops, and lemongrass.
What are the effects of myrcene?
Preclinical research suggests myrcene may promote relaxation and have anti-inflammatory properties. It's often associated with the sedating "couch-lock" effect in indica-dominant strains, though more human research is needed.
Is myrcene safe?
Myrcene is Generally Recognized as Safe (GRAS) by the FDA for food use. No significant adverse effects have been reported at levels typically found in cannabis products.
Quick Facts
- Full Name
- β-Myrcene
- Category
- monoterpene
- Boiling Point
- 332°F (167°C)
- Aroma
- Earthy, musky, clove-like
Looking for strains high in Myrcene? Our doctors can help you find the right product.
Find a DoctorRelated Terpenes
Educational Information
This content is for educational purposes only and is not medical advice. Consult a healthcare provider before using cannabis products.
Strain Variability
Terpene profiles vary significantly between batches, growers, and growing conditions—even for the same strain name. Always check lab test results.
Indica/Sativa Note
The indica/sativa distinction is largely marketing. Effects are better predicted by cannabinoid and terpene profiles than strain classification.